What is the mechanism that causes hemolytic uremic syndrome (HUS)? What are the features of HUS?
Answer: HUS occurs when Shiga-like toxin (verocytotoxin) enters the blood stream and damages the vascular endothelium. Cardinal features include thrombocytopenia, anemia, and acute renal failure.
Mnemonic:
You can get HUS from a RAT (Renal failure, Anemia, Thrombocytopenia)
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